1. It is good to budget out the cost of your aquarium. You should leave plenty of money to purchase quality filters, pumps, and heaters for your aquarium. Your big aquarium is going to do you no good if you do not have the proper equipment to keep it going.
2. Only use medication in your aquarium when you are out of other options. You should use a separate tank to medicate sick fish as some medications can have harmful effects on healthy fish.
3. You need to have some healthy natural bacteria to process the wastes and chemicals in your aquarium. This will take around 4 weeks to grow naturally, but you can purchase products to speed up the process.